منابع مشابه
Galactose metabolism in regenerating rat liver.
1. Rats trained on a controlled lighting and feeding schedule were subjected to partial hepatectomy or sham operation. 2. After a large period of about 6h the activity of UDP-galactose 4-epimerase increased threefold, reaching a maximum 4 days after partial hepatectomy, and returned to normal values within a fortnight. 3. The enzyme pattern of the UDP-galactose-glycoprotein galactosyltransferas...
متن کاملSerine metabolism in rat liver slices.
While much is known of the various pathways of serine metabolism, there is little quantitative information concerning the relative importance of each. The present study has, therefore, been undertaken to examine the over-all pattern of serine metabolism in surviving rat liver slices. It seems likely that serine is in the major pathway for both the synthesis of glycine and “l-carbon” compounds f...
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Imatinib is an orally administered tyrosine kinase inhibitor which inhibits the Bcr-Abl protein-tyrosine kinase with high selectivity. Imatinib is rapidly absorbed from the gut, after oral intake and has an almost absolute bioavailability of 98%. The metabolism of imatinib is mediated by the cytochrome P450 (CYP) isoenzymes in the liver and gut wall. CGP74588 is a major active metabolite of ima...
متن کاملPropionic acid metabolism in mouse liver slices.
Odd carbon fatty acids are considered to be oxidized in tissue by successive fl oxidation in much the same way that even carbon members of the series are (14). The terminal S-carbon unit has been investigated to some extent. Atchley (5) demonstrated propionic acid as an end-product in the oxidation of valeric acid by a rabbit enzyme system. Studies on malonate inhibition with odd carbon fatty a...
متن کاملStudies on carbohydrate metabolism in rat liver slices. VI. Hormonal factors influencing glucose-6-phosphatase.
In any consideration of carbohydrate metabolism of the liver, glucose-6phosphate plays an important r81e. Glucose must first be phosphorylated to glucose-6-phosphate in order to enter the glycolytic pathway to form glycogen and fat for storage, or to be burned for energy. On the other hand, liver phosphatase must split glucose-6-phosphate into glucose and inorganic phosphate before stored carbo...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)70605-4